Treatment of extragonadal germ cell tumors

Treatment depends on the location and type of cancer. In general, small seminomas are treated with radiation and chemotherapy largest followed by radiation. Nonseminomatous tumors usually are treated with chemotherapy followed by surgical removal of a larger tumor that remains even after chemotherapy.

Downtown area of ??the chest (mediastinum): seminomas are usually treated with high dose radiation and sometimes chemotherapy. Non-seminomas are treated with chemotherapy.

Lower back area (presacral region) and retroperitoneal tumors: chemotherapy is applied to shrink the tumor as much as possible before it is removed surgically. If the entire tumor is removed during surgery, can provide a second dose of chemotherapy, followed by a second surgery to remove the remaining leg of the tumor.

Head (pineal area): the tumor is surgically removed. Both seminomas and nonseminomas can be treated with radiation. However, since the high-dose radiation can damage different parts of the brain, some hospitals try a combination of chemotherapy with low-dose radiation, especially for non-seminomas.

As physicians are always eager to find the best treatment for rare types of cancer, your doctor may talk to you about the possibility of enrolling in a clinical trial. This is an experimental treatment program.

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