The primary invasion by the virus manifests itself in childhood and enters the nerves during the initial phase of chickenpox through sensory endings spreading along nerve trunks to the dorsal root ganglia. In the past the virus remains dormant being able to express distance of time, usually in terms of temporal decay of the state of the organism. The disease assumes a type poliradiculoneurótico with immunoallergic mechanism. There are several theories about the mechanism triggering immune (virus release by the immunogenic material, insertion of viral antigens in cell membranes, immune complex formation, direct action of the virus on the cell membrane) but currently it is still unclear what the immunoallergic actual mechanism.

From the pathological point of view there is swelling and degeneration of ganglion cells with perivascular infiltration of multinucleated cells, lymphocytes and plasmacélulas. Sometimes the inflammatory process spreads to the meninges.
Cutaneous level is observed degeneration and necrosis of cells in the basal layer of the epidermis, edema and inflammatory filtering Blisters and secondary education. The disease may manifest with symptoms such as fatigue and fever, and with local symptoms such as hyperalgesia and pain distribution “metameric”.

After 3-5 days appear in the seat of pain skin manifestations characterized by large erythematous patches that are transformed into blisters to form a crust and then scales that falls superficial scarring almost always permanent. The rash is accompanied by satellite lindoadenopatía and evolves around two weeks and the pain can persist even long after.
Complications include corneal scars (in the ophthalmic herpes) in post-herpetic paralysis (extension of the process to the anterior horns of the affected segment) and post-herpetic neuralgia.
There have been many attempts made to either pain treatment for skin lesions but especially in the prevention of complications. Following are only the attempts of ACTH and subsequent radiation and lymph, as coagulant extracted from the venom of Bthros jaraca (bothropic) Neuramidum (Neuramede), local anesthetics, “carbamazepine”, “amitriptyline” and many other drugs without But they have not achieved any progress in the therapy of this disease.

Ozone is a gas odor featurings represents an allotropic form of oxygen. Is obtained artificially by electric shock, ultraviolet radiation and electrochemical dissociation. Ozone is a powerful oxidant and exerts its action either on organic and inorganic substances with ozonuros and ozone formation. In the aqueous environment in particular, ozone molecules are decomposed with formation of oxygen continuously rising, strong oxidant and therefore very effective disinfectant it destroys bacteria, toxins and viruses (Cantarelli, 1969). Numerous experiments have shown particularly outstanding virucidal ability of ozone (Viebarn 1977, Ewell, 1941; Augurg, 1938). It is still not completely clear the mechanism of this action is believed to be linked, probably a total oxidation of viral material (Sykes, 1968). These characteristics have led to the use of ozone in the purification of water with remarkable success.

Despite all these optimal properties, has a hard time that ozone is applied as a therapeutic for humans because of the widespread belief that it was toxic, in fact ozone is only toxic if inhaled because it affects the pulmonary epithelium (Thorp, 1950). Instead suministración other routes (intramuscular, subcutaneous, endoarteriales, intravenous) did not cause any toxic effects with appropriate doses. Even in the intravenous that might seem the most dangerous by the probable formation of air emboli demonstrated safe because ozone (especially if discharge is obtained by pure oxygen, because this is not the dangerous form of nitrogen derivatives are instead form when using the air) is 15 times more soluble than pure oxygen, but instead the nitrogen is poorly soluble and therefore responsible for strokes in the air injections (Wolf, 1979).
To experience the effect of ozone on the man in viral diseases we have discussed a group of patients with herpes zoster for our study.

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